Acne Knowledge

Acne disease

Acne vulgaris (acne) is the most chronic and universal skin disease that can affect the face, neck, arms, back and chest. Acne affects almost 85% of teenagers (males and females) but individuals of all ages and genders are affected. Females continue to experience acne beyond teen years while in males acne becomes severe resulting in nodules and cysts. All ethnicities (Caucasians, African Americans, Asians and Hispanics) are at risk of developing acne. There is no cure for acne but it can be treated and minimized by using appropriate care and acne treatment products. The disease is a serious cosmetic problem, but in severe cases can affect the overall quality of life because of the disfiguring scarring of the skin and hyperpigmentation. Some individuals with severe acne develop emotional and psychological problems such as low self-esteem, humiliation, reduced social interactions and at times depression.

Types of Acne

During the acne development, the microcomedone lesion is first to appear and is considered the primary acne lesion leading to comedones and other lesions. These lesions can either be anti-inflammatory (blackheads or whiteheads) or inflammatory (papules, pustules and nodules). An increase in sebum secretion leads to cell accumulation and sloughing of dead cells that can clog the skin pores which traps sebum resulting in open and closed comedones. This provides a rich environment for P. acnes to grow and colonize with further clogging of pores and causing an inflammatory response resulting in formation of papules, pustules, and nodules.

  • Blackhead (Open comedo): Dead cells and sebum at the skin surface.
  • Whitehead (Closed comedo): A whitish bump with dead cells, sebum, and bacteria just below the skin surface.
  • Papule: Inflamed skin cell with sebum and bacteria.
  • Pustule (Pimple): Skin bump with pus containing dead cells, sebum and bacteria.
  • Nodule (Cyst): A large bump deep in the skin with pus containing dead cells, sebum and bacteria. Nodules become much harder into cysts and difficult to treat.


How does acne develop?

The skin is composed of three different layers, the epidermis, dermis and hypodermis. Acne development begins just under the top epidermal skin layer in the sebaceous glands close to our hair follicles. Sebaceous glands are a type of skin gland that secretes sebum, which is an oily substance responsible for lubricating our skin and hair. The acne development process starts with changes that affect the normal function of the sebaceous gland. Multiple factors contribute to the development of acne but four major factors in general are thought to contribute to its development and these are: an increase in sebum production, overgrowing of epidermal skin cells, sebaceous follicle inflammation, and growth of bacteria.

Hormones control the function of the sebaceous gland and hormonal imbalance is the major cause for changes in sebum production and secretion which leads to colonization and propagation of skin bacteria in the sebaceous hair follicle. The main bacteria associated with acne is Propionibacterium acnes. P. acnes releases many enzymes that breakdown sebum and produces factors that cause the infiltration and accumulation of different types of immune cells within acne. The activation and stimulation of immune cells lead to cell proliferation and secretion of proteins that cause inflammation, abnormal hyper keratinization and tissue injury. Inflammation can occur very early with cellular infiltration and accumulation of secreted proteins before hyper proliferation occurs.

Treatment of acne

Acne can be treated and minimized with systematic acne treatment regimens. Since acne cannot be cured, acne treatment has to become a routine practice to keep your skin free of acne. In case of severe acne problems (with nodules and cysts), it is recommended that you consult a physician or a dermatologist. For mild to moderate acne, over-the-counter products containing benzoyl peroxide and salicylic acid have been proven to be very effective. These two ingredients are also approved by the FDA. You should use a complete acne treatment system that works best for your acne. It is important to stay with a regimen and use the products as directed and for the recommended duration. Most of the acne treatment system available in the market should work in 6 weeks. Although there are products which contain the same active ingredients, their action is highly dependent on other ingredients in the product.

Our NugenGlo anti-acne system with its nanosize particles is designed to effectively treat mild to medium acnes. Our system has been tested and clinically proven to treat acne on the skin of different racial and ethnic backgrounds. The acne cleansing gel is unique with its dual function to cleanse as well as kill acne bacteria. It has ingredients to remove dead skin, prevent clogging of pores, promote regeneration of new skin, moisturize skin and prevent bacterial infections. The anti-acne cream kills acne causing bacteria, reduce the over secretion of sebum that clogs skin pores, promotes skin renewal and moisturization. The skin brightening cream has anti-inflammatory and anti-oxidant ingredients that brighten skin pigmentation naturally, reduce blemishes, soften and improve skin tone. You Glow with NugenGlo!